Advantra Z® Citrus aurantium Fruit Extract
Stimulates fat transport from the fat cells.
Advantra Z® Synephrine contains the stable synephrine isomer know as p-synephrine. Advantra Z® is free of m-synephrine which can cause an increase in heart rate in blood pressure in humans. Advantra Z®’s natural harvesting of p-synephrine can have up to twice the functioning ability of synthetic synephrine. The alkaloids present in Advantra Z® include synephrine, hordenine, octopamine, tyramine and N-methyltyramine. “Through orange juice levels of these agents are expressed in parts per million, or even parts per billion. That means drinking 40 or more pints of orange juice per day, or eating 80 oranges, to get the intake of the active agents that would be obtained from one or two capsules, tablets or bars containing Advantra Z®.”(33) Advantra Z® is able to increase thermogenesis in the body by stimulating beta-3 receptors. The little impact on alpha 1,2 and beta 1,2 receptors is what makes Advantra Z® able to not increase in heart rate in blood pressure in humans. A daily range between 100 and 120 milligrams of synephrine divided over 2-3 servings per day is recommended based on the product.(14) In a studied of p-synephrine on resting metabolic rate (RMR) they found that “50 milligrams of p-synephrine alone exhibited a 65 kcal increase in (RMR)”. When they did this test again by combining 50 milligrams of p-synephrine with 600 milligrams naringin it resulted in a 129 kcal increase in RMR. A third test included 50 milligrams of p-synephrine with 600 milligrams naringin and 100 milligrams of Hesperidin. The result was, the RMR increased by 183 kcal. Both of these studies were concluded with no increase in heart rate in blood pressure.(15)